Single Gene Disorder PGD

Argenomics carries the unique distinction of testing single gene disorders on embryos for the first time in India. Over the course of our journey so far, we have dealt with a large number of autosomal recessive, autosomal dominant as well as X linked disorders.

The genetic abnormality, single gene disorder happens when either both the parents are carriers of a faulty gene or one of the parent is a carrier who in turn pass the gene to his/her offspring. Genetic diseases vary as per their modes of inheritance. Argenomics can help prevent the condition passing on to children irrespective of the inheritance mode.

Examples of these relatively common single gene disorders include:

  • Thalassemia
  • Sickle Cell Anaemia
  • Hemophilia
  • Spinal Muscular Atrophy
  • Inborn errors of metabolism

Some of our PGD SGD achievements

  • Tay sachs
  • Thalassemia
  • Hemophilia
  • Smn1

One of the major reasons for the recurring pregnancy losses and IVF failures is a disorder occurring in the endometrium which mainly concerns abnormal gene expressions. Now using the procedure Endometrial Receptor Gene Assay (ERGA), it is possible to...

This is the prenatal genetic testing of foetal chromosomal aneuploidies from Mother’s Blood. We have the credit of being the first centre in the Indian subcontinent to develop in-house Non-Invasive Prenatal Testing (NIPT) which is 99.9% sensiti...

Pre-Implantation
Genetic Diagnosis (PGD)

PGD for Chromosomal Translocations: Preimplantation Genetic Diagnosis (PGD) – done on embryos created after IVF wherein the genetic diagnosis...

Pre-Implantation Genetic Screening (PGS)

24 chromosome PGS Pre-Implantation Genetic Screening (PGS) involves a process of screening of embryos in the course of In Vitro Fertilization (IVF). ...

  • cytogenetics

    Cytogenetics refers to the study of chromosome content in a cell. Argenomics has a fully equipped Cytogenetics lab with automated Karyotyping and FISH software. A complete Karyotype including structural chromosomal abnormalities and micro-deletions can be obtained using this facility. FISH is only performed on selected chromosomes. Cytogenetic studies can be done on a variety of samples like Peripheral blood, Amniotic fluid, CVS, and products of conception.

  • Hereditary Disease

    Targeted Mutation Screening  is a diagnostic tool completed through blood test that identifies the mutated gene or genes causing a genetic disease in your family. The identification of a gene mutations allows for further steps to be taken to prevent the passing on of the condition to future generations and may aid in the improvement of treatment of an affected individual. In most cases, after identifying the cause of genetic disease the couples can go with a Pre-Implantation Genetic Diagnosis (PGD) for Single Gene Disorders, a genetic test...

  • REPRODUCTIVE GENETICS

    Preconception genetic testing Pre-Implantation Genetic Screening (PGS) involves a process of screening of embryos in the course of In Vitro Fertilization (IVF). This helps to identify abnormalities in the chromosomes occurring due to aneuploidy. The main reason for recurrent IVF failures and in turn pregnancy losses is the higher risk of chromosomal errors that happ...