Reproductive Genetics

Preconception genetic testing

Pre-Implantation Genetic Screening (PGS) involves a process of screening of embryos in the course of In Vitro Fertilization (IVF). This helps to identify abnormalities in the chromosomes occurring due to aneuploidy. The main reason for recurrent IVF failures and in turn pregnancy losses is the higher risk of chromosomal errors that happen at advanced maternal age. It is in this scenario, PGS helps to ascertain the best embryos thereby improving the chances of carrying out healthy pregnancies. The success rate of an IVF attempt also increases because of this. Genetic disorders can be diagnosed before implementation. Hence, the significance of this option is attributed to the fact that the only other option could very well be the medical termination of pregnancy itself. This method ensures good health for both the newly born child as well as the mother.

Studies have shown that PGS may be most beneficial for couples meeting one of the following criteria.

• Advanced maternal age 
• Previous IVF/ICSI Failures or Recurrent implantation failures
• Chromosomal abnormalities like Mongolism
• Sex chromosomal related disorders
• Fragile X syndrome
• Male infertility related conditions

Argenomics becomes the first centre in India to have an in-house facility for PGS i.e. screening all the 23 pairs of chromosomes using the latest Ion S5 XL Next-generation sequencing platform.

Argenomics EnsureCCS+ screens all 24 chromosomes for aneuploidy. Thus, increasing your chances of achieving a healthy pregnancy and also, decreasing your risk of miscarriage by identifying embryos with the healthy number of chromosomes.

How does PGS work?

Advantages of getting PGS testing done at ARGENOMICS

When conducted the testing at Argenomics, a full embryonic Karyotype is provided with all the 23 pair screening.

Argenomics pioneers new test (Mitocount) to help select embryos which are more likely to result in viable pregnancies through In Vitro Fertilization (IVF).